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KMID : 1094020180350030077
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Journal of Veterinary Clinics
2018 Volume.35 No. 3 p.77 ~ p.82
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Reference Values of Whole Blood Viscosity and Its Correlation with Hematology and Serum Chemistry in Beagle Dogs
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Koh Jun
Lee Dong-Bin
Lee Dong-Han
Kim Nam-Soo
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Abstract
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The aim of this study was to measure whole blood viscosity (WBV) and then to establish its referencevalues and identify correlation between WBV and hematology or serum chemistry in beagle. The experiment wasmade up of 82 healthy beagle dogs. Jugular vein blood samples (10 ml) were collected. WBV (cP) measured within4 hours after collection by U-shaped scanning capillary-tube viscometer (BVD-PRO1®) which is capable of measuringyield stress and viscosity of whole blood continuously over a wide range of shear rates from 1 s?1to 1000 s?1 is newtype of capillary tube viscometer and calculates viscosity using Casson fluid model. Measured values of WBV, Completeblood cell count, serum chemistry were analyzed by RM-ANOVA test. Mean diastolic and systolic WBV (cP) were29.032 ± 6.137 and 4.528 ± 0.865. Bodyweight (BW), Red blood cell count (RBC), Hemoglobin (HGB), Hematocrit(HCT), Alkaline phosphatase (ALP), Cholestetol (CHOL), Total protein (TP), Globulin, Chloride (Cl), Fibrinogen, werestatistically correlated with WBV over whole range of shear rates (p < 0.05). This study newly evaluated referencevalues of WBV by U-shaped viscometer in beagle. Correlation between WBV and BW, RBC, HGB, HCT, ALP, CHOL,TP, Globulin, Cl, Fibrinogen was presented.
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KEYWORD
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Whole blood viscosity, Hematology, Serum chemistry, Reference values, beagle
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